de la Mata J, 2016; 94 (4): p.284-294. a) Discoid lupus erythematosus (DLE) on the right cheek and ear: scarring with…, a) “Active“ urinary sediment in lupus nephritis: if more than 5% of all…, NLM Family and twin studies in systemic lupus erythematosus. Stahl-Hallengren C, Kelley's Textbook of rheumatology. Urowitz MB, Khetarpal R, Junker P, Many patients who take these medications have positive … Gonzalez CM, Systemic lupus erythematosus is a chronic, multisystem, inflammatory disorder of autoimmune etiology, occurring predominantly in young women. American College of Pathologists. Azevedo EC, et al. Hochberg MC. Yu H, In this disease, the immune system of the body mistakenly attacks healthy tissue. Arnett FC, One author reviewed qualifying studies for relevance and method. Inflammation results in swelling, pain and other symptoms. J Rheumatol. Blanco FJ, Rodriguez-Valverde V, Treatments for mild to moderate serositis or arthritis include hydroxychloroquine, non-steroidal anti-inflammatory drugs, or corticosteroids. Swollen lymph nodes. Chng HH. See this image and copyright information in PMC. Manzi S, Leong KH, Hobbs FD, The lupus erythematosus …  |  Oliveira SK, den Ouden EJ, In lupus, however, the immune system inappropriately attacks tissues in various parts of the body. Genome scan of human systemic lupus erythematosus by regression modeling: evidence of linkage and epistasis at 4p16–15.2. et al. et al. Results from a single center. J Lab Clin Med. Guidelines for referral and management of systemic lupus erythematosus in adults. Atra E. Systemic lupus erythematosus (SLE) is an autoimmune disease that affects the skin and musculoskeletal, renal, neuropsychiatric, hematologic, cardiovascular, pulmonary, … Lupus comes from the Latin name for wolf, and the rash often seen in these patients is thought to resemble … 2000; 27:2146–51. 1997; 24:1061–5. Ginzler E, Treatment of lupus nephritis: a meta-analysis of clinical trials. 33. Chan TM, Lupus. Della Casa Alberighi O, Voss A, Gil A, 1997;145:408–15. Gladman DD, Stahl-Hallengren C, Arch Pathol Lab Med. Bresnihan B, Carneiro JR, Mortality studies in systemic lupus erythematosus. Hyland V, Molina JF, Lopez-Longo FJ, Search terms included “lupus not discoid not review not case” and “lupus and treatment and mortality,” with the following limits: 1996 to present, abstract available, human, and English language. Grennan DM, Lavilla P, Find disease activity and other lupus information for HCPs. Mok CC, Lupus is a difficult disease to diagnose, because its symptoms can be vague. 26. Bartoli E. Kelly J, systemic lupus erythematosus, classification, diagnosis, autoantibodies, nephritis Rheumatology Key messages Positive ANA is required for SLE classification and ANA remains an appropriate screening test. General symptoms associated with lupus include . Background: Systemic lupus erythematosus (SLE) is an autoimmune disease with a prevalence of 36.7/100 000 in Germany and a female/male ratio of 4:1. General symptomatology and diagnosis of systemic lupus erythematosus in adults. 4. Tetanus in Pets (Lock Jaw) The Wrath of Grapes. Urowitz MB, Renal involvement is common in systemic lupus erythematosus (SLE). Given the wide heterogeneity of clinical manifestations, several sets of classification criteria have been developed over time for epidemiological and research purposes. Nived O, The most frequently observed abnormality in patients with lupus nephritis is proteinuria . After searching several evidence-based databases (Table 1), we reviewed the MEDLINE database using the PubMed search engine. Overview of the therapy and prognosis of systemic lupus erythematosus in adults. Bascones M, New York, NY:McGraw-Hill; 2013. Diagnosis & treatment; Doctors & departments; Print. Jacobsen S, et al. Neuropsychiatric systemic lupus erythematosus (NPSLE) represents one of the most complex aspects of SLE. Lupus -- also known as systemic lupus erythematosus -- is a disease of the immune system. Systemic lupus erythematosus (SLE) is the disease most commonly mentioned, and the most serious since it involves the entire body. FitzGerald O, To date, diagnosis of SLE remains clinical with a few cases being negative for serologic tests. Kondisi yang disebut juga dengan lupus sistemik ini memiliki beberapa gejala yang khas. Font J, Mild activity can be managed with non-steroidal anti-inflammatory drugs (NSAIDs) or low-dose steroids, but more severe manifestations require prompt treatment with moderate-to-high do… Huang Q, van Suijlekom-Smit LW, To see the full article, log in or purchase access. Systemic lupus erythematosus (SLE), is the most common type of lupus. Race and gender differences. Lupus is a chronic condition, but symptoms tend to cycle in alternate periods of "flares" (or "flares-ups") and remissions. Rood MJ, Belimumab was recently approved as add-on therapy in autoantibody-positive SLE patients with high disease activity unresponsive to standard treatment. Choose a single article, issue, or full-access subscription. O'Fallon WM, Testicular Cancer in Dogs. Am J Epidemiol. Edworthy SM. In a retrospective study26 of Brazilian children, overall mortality during 16 years of follow-up was 24 percent. It is more common in African Americans and people of American Indian and Asian descent than in … Jonsen A, Gladman DD, et al. Philadelphia: Saunders, 2001:1105–19.... 2. Medicine [Baltimore]. Wright EA, 1961;57:495–511. Lupus is a systemic autoimmune disease that occurs when your body's immune system attacks your own tissues and organs. Am J Kidney Dis. Sunku J, Medsger TA Jr, (Eds). Controlled trial with chloroquine diphosphate in systemic lupus erythematosus. 1998;41:778–99. 38. Systemic Lupus Erythematosus adalah jenis lupus yang paling umum. 34. Nancy J. Olsen . Med Clin (Barc). Demonstration of LE cell: L E … LABORATORY DIAGNOSIS OF SYSTEMIC LUPUS ERYTHEMATOSUS : The hallmark of SLE is the production of autoantibodies against nuclear and few cytoplasmic components that are neither organ or species specific. More than 90% of cases of SLE occur in women, frequently starting at childbearing age. Immediate, unlimited access to all AFP content. 17. American College of Physicians Journal Club (http://www.acpjc.org), National Guideline Clearinghouse Database (http://www.guideline.gov), Agency for Healthcare Research and Quality Database (http://www.ahcpr.gov), Turning Research into Practice Database (http://www.tripdatabase.com), Cochrane Database of Systematic Reviews (http://www.cochrane.org), British National Health Service Centre for Reviews and Dissemination (http://www.york.ac.uk/inst/crd/). Petri M. A clinical and serological comparison of familial and nonfamilial systemic lupus erythematosus in Ireland. Results from a single center. Breedveld FC, 14. Gray-McGuire C, Next: Amiodarone: Guidelines for Use and Monitoring, Home Compared with adults, children have a higher incidence of malar rash, anemia, leukocytopenia,27 and severe manifestations such as neurologic or renal involvement.28. Hyland V, Nursing care of the lupus patient involves the entire family. Escalante-Triay F, Lupus. The authors thank Cheryl Mongillo and Teresa Gill Cirillo for assistance in preparing the manuscript. Incidence of systemic lupus erythematosus. The diagnosis of systemic lupus erythematosus is based on clinical and laboratory criteria. Infections and diseases of the cardiovascular, renal, pulmonary, and central nervous systems are the most frequent causes of death in patients with systemic lupus erythematosus.8,23,32–37 Since the 1950s, the five-year survival rate for patients with systemic lupus erythematosus has increased from 50 percent to a range of 91 to 97 percent.8,23,32–34,38,39 It is not known how much of this increase in survival is due to improved management versus diagnosis of earlier and milder disease. III. In: Ruddy S, Harris ED, Sledge CB, Kelley WN, eds. 2003 Dec 1;68(11):2179-2187. Systemic lupus erythematosus (SLE) is a chronic autoimmune disease in which the body’s immune system attacks and causes inflammation in its own tissues. Junker P, Undiagnosed systemic lupus erythematosus in the community. Systemic lupus erythematosus (also known as SLE) is characterised by flare ups and periods of improvement (remissions), and can can affect almost any organ or system of the body. 2000;27:680–4. Specifically, false-positive rates will be higher in populations with a low prevalence of the disease, such as primary care patients. During the last decades, there has been an increased interest in the discovery and validation of biomarkers that reliably reflect specific aspects of lupus. Rodriguez-Mahou M, Hospital experience and expected mortality in patients with systemic lupus erythematosus: a hospital level analysis. Symptoms vary between people and may be mild to severe. 29. Disease mortality and clinical factors of prognostic value. Therefore, a positive result helps to establish the diagnosis of the disease, but a negative result does not rule it out.46 The CAP guideline recommends against testing for other autoantibodies in ANA-positive patients, because there is little evidence that these tests are of benefit.46, The ACR recommends that primary care physicians consider a rheumatology referral for patients with characteristic signs and symptoms of systemic lupus erythematosus (Table 2)2,20,21 and a positive ANA test, particularly if these patients have more than mild or stable disease.2 [Reference2—Evidence level C, consensus/expert guidelines]. Schur PH. Pego-Reigosa JM, Rúa-Figueroa Í, López-Longo FJ, Galindo-Izquierdo M, Calvo-Alén J, Olivé-Marqués A, del Campo V, García-Yébenes MJ, Loza-Santamaría E, Blanco R, Melero-González R, Vela-Casasempere P, Otón-Sánchez T, Tomero-Muriel E, Uriarte-Isacelaya E, Fito-Manteca MC, Freire-González M, Narváez J, Fernández-Nebro A, Zea-Mendoza A, Rosas J; RELESSER Group, from the Spanish Society of Rheumatology Systemic Autoimmune Diseases Study Group (EASSER). Johnson AE, Lee FA. et al. 1. Khamashta MA, Goldsmith CH, Morbidity and mortality in systemic lupus erythematosus during a 5-year period. Atra E. Retrieved March 20, 2003, from http://www.uptodate.com/physicians/rheumatology_toclist.asp. 1997;34:979–86. Diagnosing lupus is difficult because signs and symptoms vary considerably from person to person. Clinical heterogeneity, unpredictable course and flares are characteristics of systemic lupus erythematosus (SLE). Lupus. Treatment of systemic lupus erythematosus: an update. et al. When ANA titers are measured, laboratories should report ANA levels at both 1:40 and 1:160 dilutions and should supply information on the percentage of normal persons who are positive at each dilution.41, Interpretation of ANA titers is similar in children. Monteagudo I, et al. Kark RM. 10. JAMES M. GILL, M.D., M.P.H., Christiana Care Health Services, Wilmington, Delaware, PETER V. ROCCA, M.D., Wilmington, Delaware, DENE T. WALTERS, M.D., Christiana Care Health Services, Wilmington, Delaware. Gladman DD, Clinical and immunological profile of SLE: some unusual features. Moser KL, et al. Systemic Lupus Erythematosus (SLE) in Dogs. Pirani CL, Dr. Gill received a medical degree from the University of Medicine and Dentistry of New Jersey–Robert Wood Johnson Medical School, Piscataway, and a master of public health degree from Johns Hopkins University, Baltimore.... ANNA M. QUISEL, M.D., is a family practice and urgent care physician in the Newark, Del., area. Escalante-Triay F, Spindler A, No screening studies on the prevalence of systemic lupus erythematosus in children were identified. Scand J Rheumatol. 1998;17:478–84. Abu-Shakra M, The Systemic Lupus International Collaborating Clinics/American College of Rheumatology (SLICC/ACR) damage index for systemic lupus erythematosus international comparison. . Arthritis Rheum. Lupus. A biopsy of … Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States. Racanelli V, Overview. Sosa-Munoz J, Learn more about the symptoms, complication, causes, types, diagnosis, treatment, lifestyle changes, and outlook for lupus. 1997;29:193–9. Grennan DM, One review14 estimated the overall U.S. prevalence of definite systemic lupus erythematosus plus incomplete systemic lupus erythematosus (disease meeting only some diagnostic requirements for systemic lupus erythematosus) to be 40 to 50 cases per 100,000 persons. Other studies21,32,43 have reported sensitivities ranging from 78 to 96 percent and specificities ranging from 89 to 100 percent. et al. Fries JF, Systemic onset juvenile rheumatoid arthritis. Boedecker SC, Philippi KFA, Neuberger E, Schmidt S, Pfirrmann D, Haller N, Schwarting A, Simon P, Weinmann-Menke J. JMIR Res Protoc. Carreno L, Rood MJ, A study41 involving 15 international laboratories found that ANA tests in the general population were positive in 32 percent of persons at a 1:40 dilution and in 5 percent of persons at a 1:160 dilution. Helmick CG, Reveille J, A multicentre study of 513 Danish patients with systemic lupus erythematosus. It is more common in African Americans and people of American Indian and Asian descent than in white people. Lupus QoL-US benchmarks for US patients with systemic lupus erythematosus. 1997;24:1072–4. 1995;38:1260–70. When meta-analyses or systematic reviews were identified, they were used instead of the original research articles. Manolios N, How lupus is diagnosed. Systemic lupus erythematosus, lupus nephritis and end-stage renal disease: a pragmatic review mapping disease severity and progression. Akan tetapi, nyatanya gejala Systemic Lupus Erythematosus sering kali mirip dengan penyakit umum lainnya, sehingga SLE ini sulit untuk didiagnosis. SLE is characterized by the production of unusual antibodies in the blood. Lucero E, No one test can diagnose lupus. Petri M. Rev Rhum Engl Ed. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus [Letter]. This site needs JavaScript to work properly. Improved survival over 24 years. Sources of funding: this project was partially funded by the Delaware Division of Public Health, grant number PSC0432. A more recent article on systemic lupus erythematosus is available. Deyo RA, Rothfield NF, Remission of systemic lupus erythematosus is not uncommon but often is punctuated by flares.31 In a six-year prospective cohort study,23 disease flares occurred at a rate of 0.2 per year per patient. 1982;25:1271–7. 11. A multicenter study. 3. et al. Nived O, PETER V. ROCCA, M.D., is a rheumatologist in private practice in Wilmington, Del. This article reviews evidence-based recommendations for the diagnosis of systemic lupus erythematosus by primary care physicians. van Suijlekom-Smit LW, Della Casa Alberighi O, Sources of funding: this project was partially funded by the Delaware Division of Public Health, grant number PSC0432, The authors thank Cheryl Mongillo and Teresa Gill Cirillo for assistance in preparing the manuscript. Twelve-Week Internet-Based Individualized Exercise Program in Adults With Systemic Lupus Erythematosus: Protocol for a Randomized Controlled Trial. low-grade fever, loss of appetite, nausea, muscle aches, joint pains, fatigue. Systemic Lupus Erythematosus (SLE) diagnosis is positive if: Patient has biopsy-proven nephritis compatible with SLE and Antinuclear antibody (ANA) or anti-dsDNA antibodies. Guidelines for referral and management of systemic lupus erythematosus in adults. systemic lupus erythematosus, classification, diagnosis, autoantibodies, nephritis Rheumatology Key messages Positive ANA is required for SLE classification and ANA remains an appropriate screening test. Corrales A, Many pharmacologic agents have been associated with a lupuslike syndrome (see see Drug-Induced Lupus Erythematosus), but procainamide, hydralazine, and isoniazid have been studied the most extensively. American College of Rheumatology Ad Hoc Committee on Systemic Lupus Erythematosus Guidelines. Medicine [Baltimore]. This content is owned by the AAFP. Treatment of lupus nephritis: a meta-analysis of clinical trials. Physicians can use the Physician's Global Assessment (PGA), Systemic Lupus Erythematosus Disease Activity Index (SLEDAI)*, and British Isles Lupus Assessment Group (BILAG) to measure changes in SLE disease activity. If patients with a normal ANA titer develop new clinical features that are consistent with systemic lupus erythematosus, ANA testing should be repeated.46 [Evidence level C, consensus/expert guidelines], According to a guideline from the College of American Pathologists (CAP), no further laboratory tests are necessary in patients who meet diagnostic criteria for systemic lupus erythematosus and also have a positive ANA test result.46, Testing for antibody to double-stranded DNA antigen (anti-dsDNA) and antibody to Sm nuclear antigen (anti-Sm) may be helpful in patients who have a positive ANA test but do not meet full criteria for the diagnosis of systemic lupus erythematosus. The clinical course is variable, with a broad spectrum of organ manifestations; lupus nephritis develops in about half of all patients. Mackinnon MJ. Sturfelt G. Casatta L, Ramsey-Goldman R, We conducted a systematic evidence-based review of the published literature on systemic lupus erythematosus. The most useful tests identify certain autoantibodies that are often present in the blood of lupus patients. Undiagnosed systemic lupus erythematosus in the community. Epub 2013 Oct 29. The diagnosis of systemic lupus erythematosus is made based on a combination of typical clinical manifestations and positive serologies. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. Contribution of traditional risk factors to coronary artery disease in patients with systemic lupus erythematosus. 1997;6:27–31. OR. Death occurred because of infection (58 percent), central nervous system disease (36 percent), and renal disease (7 percent). Lehman TJ. Hospital experience and expected mortality in patients with systemic lupus erythematosus: a hospital level analysis. Antibodies to DNA in patients with systemic lupus erythematosus: their role in the diagnosis, the follow-up and the pathogenesis of the disease. Retrieved March 20, 2003, from. Systemic lupus erythematosus is a multisystem inflammatory disease that is often difficult to diagnose. Kelly J, A multicentre study of 513 Danish patients with systemic lupus erythematosus. Corrales A, Deyo RA, Guidelines for clinical use of the antinuclear antibody test and tests for specific autoantibodies to nuclear antigens. Application of the 1982 revised criteria for the classification of systemic lupus erythematosus on a cohort of 346 Norwegian patients with connective tissue disease. He completed an internal medicine residency at Christiana Care Health Services and a rheumatology fellowship at Georgetown University School of Medicine. Dall’Era M. Systemic lupus erythematosus. Felson DT, Sato EI. Marwaha RK, et al. Systemic lupus erythematosus (SLE), also known as lupus, is an autoimmune disease where the immune system mistakenly attacks healthy tissues throughout the body. Mortality studies in systemic lupus erythematosus. Trends in the incidence and mortality of systemic lupus erythematosus, 1950–1992. Application of the 1982 revised criteria for the classification of systemic lupus erythematosus on a cohort of 346 Norwegian patients with connective tissue disease. Sato EI, McCarty DJ, McShane DJ, Z Rheumatol. Inflammation caused by lupus can affect many different body systems — including your joints, skin, kidneys, blood cells, brain, heart and lungs. FitzGerald O, Felson DT, Nived O, Parfitt A, Sign up for the free AFP email table of contents. Tracheal Collapse in Dogs . Andrade LE, Skin changes that give the disease its name manifest nearly as often. Ferraz MB, Cunnane G, Copyright © 2020 American Academy of Family Physicians. Arthritis Rheum. Incidence studies of systemic lupus erythematosus in southern Sweden: increasing age, decreasing frequency of renal manifestations and good prognosis. Khamashta MA, The most common forms of lupus are milder forms, and most people enjoy a full life, even … In the United States, systemic lupus erythematosus is reported to be more common in women, particularly black women, than in white men.14,16 One U.S. retrospective study16 of medical records found that the disease is diagnosed 23 times more often in black women than in white men. Rivest C, Systemic lupus erythematosus (SLE) is an autoimmune disease. Systemic lupus erythematosus diagnosis and management Bernard Thong, Bernard Thong 1 Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore, Republic of Singapore. Double blind, randomized, placebo controlled clinical trial of methotrexate in systemic lupus erythematosus. American College of Rheumatology Ad Hoc Committee on Clinical Guidelines. Blanco FJ, Gaffney PM, The last diagnosis was confirmed by physical examination. 18. Cobarrubias-Cobos A, Sturfelt G. Bromocriptine in systemic lupus erythematosus: a double-blind, randomized, placebo-controlled study. One author reviewed qualifying studies for relevance and method. Systemic lupus erythematosus (SLE) is the most common form of lupus — 70 % of people with lupus have it. Fortin P, Rahman P, 1997;13:93–8. Search terms included lupus not discoid not review not case and lupus and treatment and mortality, with the following limits: 1996 to present, abstract available, human, and English language. Genest J Jr. Association between clinical factors, socioeconomic status, and organ damage in recent onset systemic lupus erythematosus. Antinuclear antibody titer is the primary laboratory test used to diagnose systemic lupus erythematosus. Because diagnosis can be challenging, it is important to see a doctor specializing in rheumatology for a final diagnosis. Family and twin studies in systemic lupus erythematosus. Lawrence RC, Huang Q, Methods: Masi AT, Jansen-McWilliams L, Helmick CG, 41. Kavanaugh A, Husby G. USA.gov. Meinao IM, 1989;68:141–50. General symptomatology and diagnosis of systemic lupus erythematosus in adults. 37. Gilboe IM, 25. 2013 Aug;72(6):575-80. doi: 10.1007/s00393-013-1213-y. Hochberg MC. (ANA = antinuclear antibody; ACR = American College of Rheumatology; antidsDNA = antibody to double-stranded DNA antigen; anti-Sm = antibody to Sm nuclear antigen). 11(December 1, 2003) 1997 Update of the 1982 American College of Rheumatology Revised Criteria for Classification of Systemic Lupus Erythematosus. II. [Management of systemic lupus erythematosus]. Rivest C, Systemic lupus erythematosus (lupus) is a chronic (long-lasting) autoimmune disease that can affect many parts of the body. Schur PH. Want to use this article elsewhere? Before making a diagnosis of systemic lupus erythematosus (SLE), ruling out drugs as the cause of the condition is important. McGrath H, Lupus, technically known as systemic lupus erythematosus (SLE), is an autoimmune disease in which the body's immune system mistakenly attacks healthy tissue in many parts of the body. Arch Dis Child. Immunological and clinical differences between juvenile and adult onset of systemic lupus erythematosus. Although SLE is—by and large—a systemic disease, occasionally it can be organ-dominant, posing diagnostic challenges. This material may not otherwise be downloaded, copied, printed, stored, transmitted or reproduced in any medium, whether now known or later invented, except as authorized in writing by the AAFP. Symptoms of systemic lupus erythematosus (SLE, often referred to as simply lupus) can be quite different, because there are different types of lupus, and not all affected people show the same symptoms. 1997 Update of the 1982 American College of Rheumatology Revised Criteria for Classification of Systemic Lupus Erythematosus. In one study41 that used patients with connective tissue diseases as the control group, the revised ACR diagnostic criteria for systemic lupus erythematosus were found to have an overall sensitivity of 96 percent and a specificity of 96 percent. Casatta L, Chng HH. Solomon DH, LaPorte RE, Wright EA, et al. The clinical manifestations of systemic lupus erythematosus are fundamentally the same in children and adults.15 In two descriptive studies25,26 of children with the disease, the most frequent manifestations were fever, rash, arthritis, alopecia, and renal involvement. 9. LABORATORY DIAGNOSIS OF SYSTEMIC LUPUS ERYTHEMATOSUS : The hallmark of SLE is the production of autoantibodies against nuclear and few cytoplasmic components that are neither organ or species specific. 2000;9:377–81. Farewell VT. Dr. Walters is a graduate of the University of Pennsylvania School of Medicine, Philadelphia. Nived O, Gourley IS, Azevedo EC, Gilboe IM, Information from references 2,20,21,41, and 42. A multicenter prospective study of 1,000 patients. / 2015 Jun;24(7):720-9. doi: 10.1177/0961203314563818. Cohen AS, 1999;28:222–6. J Rheumatol. A multicenter prospective study of 1,000 patients. Cervera R, Jonsen A, Evaluation of the 1982 ARA lupus criteria data set in pediatric patients. 1999; 26:1275–9. Dr. Quisel graduated from the University of Washington School of Medicine, Seattle, and completed a family practice residency at Christiana Care Health Services. The overall aim of therapy is to control disease activity. 46. 40. Clinical heterogeneity, unpredictable course and flares are characteristics of systemic lupus erythematosus (SLE). 1999;28:81–7. Higher mortality rates are associated with seizures, lupus nephritis, and azotemia.36,37,40. Leong KH, In: Ruddy S, Harris ED, Sledge CB, Kelley WN, eds. Lupus. Arthritis Rheum. Anti-dsDNA and anti-Smith antibodies are highly specific for SLE Smeenk R, Brinkman K, van den Brink H, et al. Tremoring or Shivering in Dogs. Evaluation of the 1982 ARA lupus criteria data set in pediatric patients. Georgetown University School of Medicine, Washington, D.C almost any organ and is characterized by pathogenic autoantibodies... Delaware Division of Public Health, grant number PSC0432, Homburger HA FC, Deyo RA Sequeira! 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